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DRUG DISCOVERY
BUSINESS DEVELOPMENT
Manager, Microbial upstream fermentation
Suzhou
Doctor of Philosophy Degree
2024-11-01
1. Responsible for the development and optimization of fermentation processes for laboratory platform strains such as Escherichia coli and yeast, including fermentation data analysis and evaluation of fermentation parameters.
2. Responsible for the formulation and implementation of fermentation plans and processes, project advancement, completion of small-scale development, resolving key issues encountered during R&D, and completing R&D reports and process description documents.
3. Responsible for scaling up and stabilizing production processes, drafting and updating batch production records, and reviewing related production technical documents and operational records.
4. Responsible for process control and risk management in the upstream processes, as well as optimizing and continuously improving workflows during production.
5. Leading the team to complete microbiological fermentation and harvesting operations in accordance with GMP requirements, ensuring timely execution of production plans.
6. Leading investigations of process deviations and impact assessments, developing preventive and corrective measures, and supervising the implementation of these actions.
7. Responsible for drafting and reviewing the overall process validation plan. Leading, preparing, and executing process performance confirmation activities, including preparing plans and reports.
8. Supporting the implementation of downstream production processes and providing other necessary support.
9. Completing other relevant tasks assigned by superiors.
1. PhD in relevant fields such as bioengineering, biotechnology, biological sciences, or fermentation engineering, with expertise in microbial metabolism and fermentation principles.
2. Over 5 years of production experience in microbial cell USP related to PD or GMP environments.
3. Experience in successfully developing and scaling up E. coli or yeast fermentation processes to GMP production, along with experience in fermentation data analysis and parameter evaluation.
4. Experience in constructing a tier-3 E. coli cell bank is preferred.
5. Proficient in operating small-scale and pilot-scale fermentation equipment and related systems, including strain activation, batch feeding, and fed-batch operations.
6. Strong understanding of fermentation experimental principles and operations, including sterilization, aseptic techniques, and fermentation processes.
7. Proficient in the basic principles, usage, and maintenance of fermentation-related equipment, such as sterilizers, biosafety cabinets, and fermenters.
8. Capable of designing single-factor experiments and DOE, including complete optimization experiments for shake-flask and fermenter stages, with the ability to accurately analyze and interpret results.
9. Strong planning and coordination skills for experiments, able to reasonably allocate personnel and lead the team in executing experiments.
Scientist, Synthetic biology
Suzhou
Doctor of Philosophy Degree
2024-11-01
1. Responsible for completing protein transformation projects through molecular and biochemical knowledge.
2. Cooperate with the drug development team to serve projects.
1.PhD degree in biochemistry and molecular biology, genetics, microbiology.
2.Fluent in speaking and writing in English.
3.Experience in enzyme modification is preferred.
4.Proficient in operating molecular cloning and protein purification experiments.
5. Independently design and carry out project-related biochemical experiments.
6. Broad knowledge about biology, in order to facilitate the design of enzyme modification related experiments in many aspects.
Email: Talent@genequantum.com
Scientist, Chemical biology
Suzhou
Doctor of Philosophy Degree
2024-11-01
1. Participate in the research and development, project establishment and promotion of some new technologies or new products.
2. Independently or lead R&D team to tackle difficult projects and ensure project progress.
3. According to the project plan, independently consult the literature and formulate the synthesis route.
4. Skillfully complete chemical reactions, analyze problems encountered in experiments and propose reasonable solutions.
5. Write the experimental records and reports clearly and completely.
6. Assist supervisor to complete the project progress report and participate in the communication with customers.
7. Participate in the daily management of the laboratory.
1. PhD degree in organic chemistry, medicinal chemistry, chemical biology and so on.
2. Highly skilled synthetic chemist with the ability of design and conduction of organic experiment.
3. Synthesize organic compounds with multi steps independently.
4. Fluent in speaking and writing in English.
5.Self-motivated and the proven ability to learn new techniques, to problem solve, and to have a good record of productivity.
Email: Talent@genequantum.com
Scientist, Tumor immunology
Suzhou
Doctor of Philosophy Degree
2024-11-01
1. Routine cell culture, cell line construction and maintenance.
2.Designed and completed drug activity evaluation and screening tests in vitro, analyzed and summarized test data, and wrote reports.
3.Design and complete in vitro mechanism study of drugs.
4.Responsible for the literature research, task assignment, data interpretation and problem solving of pharmacological experiments.
5.Undertake the early literature research of some innovative projects, and provide constructive suggestions for innovative projects.
6.Responsible for the docking management of CRO.
7.Complete assigned public affairs and routine maintenance work.
1.PhD degree in pharmaceutical science, biochemistry, chemistry, biology,and so on.
2.Experience in GraphPad data analysis, Flow CytoMetry, ADCC, WB, PCR, immunohistochemistry and immunofluorescence is preferred.
Email: Talent@genequantum.com